Antifungal activity of Trillium grandiflorum constituents

J Nat Prod. 1988 Jan-Feb;51(1):94-8. doi: 10.1021/np50055a013.

Abstract

EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antifungal Agents / pharmacology*
  • Antifungal Agents / therapeutic use
  • Antifungal Agents / toxicity
  • Candidiasis / drug therapy
  • Fungi / drug effects
  • Magnetic Resonance Spectroscopy
  • Mice
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plant Extracts / toxicity
  • Plants, Medicinal / analysis*

Substances

  • Antifungal Agents
  • Plant Extracts