Increased 68Ga-FAPI-04 Uptake in Schmorl Node in a Patient With Gastric Cancer

Clin Nucl Med. 2021 Aug 1;46(8):700-702. doi: 10.1097/RLU.0000000000003623.

Abstract

A 78-year-old man with a newly diagnosed gastric adenocarcinoma underwent 18F-FDG and 68Ga-FAPI-04 PET/CT before treatment. Both 18F-FDG and 68Ga-FAPI-04 PET/CT demonstrated intense radioactivity in the gastric cancer. However, the benign Schmorl node in the inferior endplate of the T5 vertebrae showed increased uptake of 68Ga-FAPI-04, which was not FDG avid. Two months after radical gastrectomy of the gastric cancer (pT1aN0M0, IA), a follow-up CT showed that the Schmorl node in T5 vertebrae remained unchanged.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biological Transport
  • Fluorodeoxyglucose F18 / metabolism
  • Gastrectomy
  • Humans
  • Male
  • Nucleus Pulposus / diagnostic imaging
  • Nucleus Pulposus / metabolism*
  • Positron Emission Tomography Computed Tomography
  • Quinolines / metabolism*
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / metabolism*
  • Stomach Neoplasms / surgery

Substances

  • 68Ga-FAPI
  • Quinolines
  • Fluorodeoxyglucose F18