Developing a method that can effectively define and sort cancer stem cells (CSCs) is extremely desirable. Mechanical stiffness is of paramount importance for a cell to differentiate and can reflect the differentiation state of cells. In line with this notion, cell softness is identified to be a unique marker for highly tumorigenic CSCs.
Keywords: B-cell CLL/lymphoma 9-like (BCL9L); Cancer stem cells (CSCs); marker; softness.
© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.