Impacts of Short-Term Fine Particulate Matter Exposure on Blood Pressure Were Modified by Control Status and Treatment in Hypertensive Patients

Zhennan Lin; Xinyan Wang; Fangchao Liu; Xueli Yang; Qiong Liu; Xiaolong Xing; Jie Cao; Jianxin Li; Keyong Huang; Weili Yan; Tingting Liu; Meng Fan; Wei Li; Shufeng Chen; Xiangfeng Lu; Dongfeng Gu; Jianfeng Huang

doi:10.1161/HYPERTENSIONAHA.120.16611

Impacts of Short-Term Fine Particulate Matter Exposure on Blood Pressure Were Modified by Control Status and Treatment in Hypertensive Patients

Hypertension. 2021 Jul;78(1):174-183. doi: 10.1161/HYPERTENSIONAHA.120.16611. Epub 2021 Jun 1.

Authors

Zhennan Lin^#^{1

2}, Xinyan Wang^#^{1

2

3}, Fangchao Liu^{1

2}, Xueli Yang⁴, Qiong Liu^{1

2}, Xiaolong Xing^{1

2}, Jie Cao^{1

2}, Jianxin Li^{1

2}, Keyong Huang^{1

2}, Weili Yan⁵, Tingting Liu⁶, Meng Fan⁷, Wei Li⁸, Shufeng Chen^{1

2}, Xiangfeng Lu^{1

2}, Dongfeng Gu^{1

9

2

10}, Jianfeng Huang^{1

2}

Affiliations

¹ Department of Epidemiology (Z.L., X.W., F.L., Q.L., X.X., J.C., J.L., K.H., S.C., X.L., D.G., J.H.), Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
² Key Laboratory of Cardiovascular Epidemiology, Chinese Academy of Medical Sciences, Beijing, China (Z.L., X.W., F.L., Q.L., X.X., J.C., J.L., K.H., S.C., X.L., D.G., J.H.).
³ Center for Reproductive Medicine, Tianjin Central Hospital of Gynecology Obstetrics, China (X.W.).
⁴ Tianjin Key Laboratory of Environment, Nutrition and Public Health, Department of Occupational and Environmental Health, School of Public Health, Tianjin Medical University, China (X.Y.).
⁵ Department of Clinical Epidemiology and Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China (W.Y.).
⁶ Department of Cardiology, Renmin Hospital of Wuhan University, China (T.L.).
⁷ State Key Laboratory of Remote Sensing Science, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing, China (M.F.).
⁸ Function Test Center (W.L.), Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
⁹ State Key Laboratory of Cardiovascular Disease (D.G.), Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
¹⁰ School of Medicine, Southern University of Science and Technology, Shenzhen, China (D.G.).

^# Contributed equally.

PMID: 34058854
DOI: 10.1161/HYPERTENSIONAHA.120.16611

Abstract

[Figure: see text].

Keywords: angiotensin receptor antagonists; blood pressure control; blood pressure monitoring, ambulatory; hypertension; hypotension.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Angiotensin Receptor Antagonists / therapeutic use
Blood Pressure / drug effects
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory / methods
Environmental Exposure / adverse effects*
Environmental Exposure / analysis
Female
Humans
Hypertension / etiology
Hypertension / physiopathology*
Hypertension / prevention & control
Male
Middle Aged
Particulate Matter / adverse effects*
Particulate Matter / analysis
Risk Factors
Seasons
Surveys and Questionnaires
Time Factors

Substances

Angiotensin Receptor Antagonists
Particulate Matter