Synchronous, Yet Genomically Distinct, GIST Offer New Insights Into Precise Targeting of Tumor Driver Mutations
JCO Precis Oncol
.
2021 Mar 19:5:PO.20.00384.
doi: 10.1200/PO.20.00384.
eCollection 2021.
Authors
Eleftherios A Makris
1
2
,
Ashwyn K Sharma
1
2
,
Erik N Bergstrom
3
4
,
Xiaojun Xu
2
5
,
Jorge de la Torre
1
2
,
Sudeep Banerjee
2
6
,
Vi Nguyen
1
2
,
Mojgan Hosseini
7
,
Adam Burgoyne
2
8
,
Olivier Harismendy
2
5
,
Ludmil B Alexandrov
2
3
4
,
Jason K Sicklick
1
2
Affiliations
1
Department of Surgery, Division of Surgical Oncology, UC San Diego School of Medicine, San Diego, CA.
2
Moores Cancer Center, UC San Diego, La Jolla, CA.
3
Department of Cellular and Molecular Medicine, UC San Diego School of Medicine, San Diego, CA.
4
Department of Bioengineering, UC San Diego Jacobs School of Engineering, San Diego, CA.
5
Department of Medicine, Division of Biomedical Informatics, UC San Diego School of Medicine, San Diego, CA.
6
Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.
7
Department of Pathology, UC San Diego School of Medicine, San Diego, CA.
8
Department of Medicine, Division of Hematology-Oncology, UC San Diego School of Medicine, San Diego, CA.
PMID:
34250403
PMCID:
PMC8232556
DOI:
10.1200/PO.20.00384
No abstract available
Publication types
Case Reports
MeSH terms
Gastrointestinal Stromal Tumors / genetics*
Genome
High-Throughput Nucleotide Sequencing
Humans
Jejunal Neoplasms / genetics*
Male
Middle Aged
Mutation*
Stomach Neoplasms / genetics*
Grants and funding
T32 CA121938/CA/NCI NIH HHS/United States