Acetoxymethyl-methylnitrosamine (AMMN) induced colorectal carcinogenesis is stimulated by chronic alcohol consumption

Alcohol Alcohol Suppl. 1987:1:501-2.

Abstract

Chronic ethanol feeding together with the direct acting carcinogen AMMN led to an earlier occurrence of colorectal tumors in SD rats.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Colonic Neoplasms / chemically induced*
  • Dimethylnitrosamine / analogs & derivatives*
  • Dimethylnitrosamine / pharmacology
  • Drug Synergism
  • Ethanol / adverse effects*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Rectal Neoplasms / chemically induced*

Substances

  • Ethanol
  • methyl(acetoxymethyl)nitrosamine
  • Dimethylnitrosamine