A Woman With Hypertriglyceridemia Who Acquired Antibody Against GPIHBP1

Yuka Hirano; Yasunori Suematsu; Yuiko Yano; Shuichi Sato; Shin-Ichiro Miura

doi:10.1016/j.jaccas.2019.11.052

A Woman With Hypertriglyceridemia Who Acquired Antibody Against GPIHBP1

JACC Case Rep. 2020 Jan 15;2(1):15-18. doi: 10.1016/j.jaccas.2019.11.052. eCollection 2020 Jan.

Authors

Yuka Hirano¹, Yasunori Suematsu¹, Yuiko Yano¹, Shuichi Sato², Shin-Ichiro Miura¹

Affiliations

¹ Department of Cardiology, School of Medicine, Fukuoka University, Fukuoka, Japan.
² Futata Tetsuhiro Clinic, Fukuoka, Japan.

Abstract

We report a case of a woman with primary hypertriglyceridemia caused by acquired glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 (GPIHBP1) autoantibody. This case highlights the necessity of detecting GPIHBP1 autoantibody in patients with acquired hypertriglyceridemia. (Level of Difficulty: Intermediate.).

Keywords: GPIHBP1; GPIHBP1, glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1; HDL, high-density lipoprotein; LDL, low-density lipoprotein; LPL, lipoprotein lipase; VLDL, very low-density lipoprotein; autoantibody; hypertriglyceridemia.

Publication types

Case Reports