There and back again: malaria parasite single-cell transcriptomics comes full circle

Christopher Nötzel; Björn F C Kafsack

doi:10.1016/j.pt.2021.07.011

There and back again: malaria parasite single-cell transcriptomics comes full circle

Trends Parasitol. 2021 Oct;37(10):850-852. doi: 10.1016/j.pt.2021.07.011. Epub 2021 Aug 12.

Authors

Christopher Nötzel¹, Björn F C Kafsack²

Affiliations

¹ Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; Biochemistry, Cell and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA.
² Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. Electronic address: bjk2007@med.cornell.edu.

Abstract

The Malaria Cell Atlas (MCA) is an ambitious, ongoing project to profile the intensity and heterogeneity of gene expression throughout the entire malaria parasite life cycle with single-cell resolution. Real et al. now complete the cycle by adding the transmission stages of the most virulent malaria parasite, Plasmodium falciparum, to this easy-to-use resource.

Keywords: cell atlas; malaria; parasite; scRNA-seq; single-cell transcriptomics.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Animals
Malaria*
Parasites*
Plasmodium falciparum / genetics
Transcriptome

Abstract

Publication types

MeSH terms

Grants and funding