Mitochondrial-derived compartments: A "fusel alcohol generator" in yeast?

Tim König; Heidi M McBride

doi:10.1016/j.molcel.2021.08.032

Mitochondrial-derived compartments: A "fusel alcohol generator" in yeast?

Mol Cell. 2021 Sep 16;81(18):3670-3671. doi: 10.1016/j.molcel.2021.08.032.

Authors

Tim König¹, Heidi M McBride²

Affiliations

¹ Montreal Neurological Institute, McGill University, 3801 University Ave., Montreal, QC H3A 2B4, Canada.
² Montreal Neurological Institute, McGill University, 3801 University Ave., Montreal, QC H3A 2B4, Canada. Electronic address: heidi.mcbride@mcgill.ca.

PMID: 34547230
DOI: 10.1016/j.molcel.2021.08.032

Abstract

Schuler et al. (2021) demonstrate that mitochondrial-derived compartments protect cells from amino acid toxicity by activation of amino acid catabolism through the Ehrlich pathway, thus highlighting the incredible plasticity of mitochondria in rewiring cellular metabolism.

Publication types

Comment

MeSH terms

Alcohols
Mitochondria
Saccharomyces cerevisiae Proteins* / genetics
Saccharomyces cerevisiae* / genetics

Substances

Alcohols
Saccharomyces cerevisiae Proteins