Mapping thyrotropin beta subunit gene in man and mouse

Somat Cell Mol Genet. 1986 May;12(3):307-11. doi: 10.1007/BF01570791.

Abstract

Thyrotropin (TSH) is composed of two subunits: alpha and beta. Previously, we have mapped the TSH alpha gene to human chromosome 6 and mouse chromosome 4. In this study we have located the human TSH beta gene on chromosome 1 and the mouse TSH beta gene to chromosome 3. These data suggest that the TSH beta gene lies in a conserved linkage group with the genes for amylase 1 and 2, nerve growth factor, and the protooncogene Nras.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping
  • Chromosomes, Human, 1-3*
  • Cloning, Molecular
  • DNA / genetics
  • Genetic Linkage
  • Humans
  • Hybrid Cells
  • Mice / genetics*
  • Nucleic Acid Hybridization
  • Thyrotropin / genetics*

Substances

  • Thyrotropin
  • DNA