Hemorrhagic Fever with Renal Syndrome - Liaoning Province, China, 1999-2018

Cui Shang; Yingwei Sun; Qiangling Yin; Xiaoxia Huang; Xuesheng Liu; Quanfu Zhang; Lingling Mao; Chuan Li; Aqian Li; Qin Wang; Lina Sun; Mifang Liang; Shiwen Wang; Dexin Li; Jiandong Li

doi:10.46234/ccdcw2020.091

Hemorrhagic Fever with Renal Syndrome - Liaoning Province, China, 1999-2018

China CDC Wkly. 2020 May 15;2(20):350-354. doi: 10.46234/ccdcw2020.091.

Authors

Cui Shang¹, Yingwei Sun², Qiangling Yin¹, Xiaoxia Huang¹, Xuesheng Liu², Quanfu Zhang¹, Lingling Mao², Chuan Li¹, Aqian Li¹, Qin Wang¹, Lina Sun¹, Mifang Liang¹, Shiwen Wang¹, Dexin Li¹, Jiandong Li¹

Affiliations

¹ Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
² Institute for prevention and control of infection and infectious diseases, Center for Disease Control and Prevention of Liaoning Province, Shenyang, Liaoning, China.

Abstract

What is already known on this topic?

Hemorrhagic fever with renal syndrome (HFRS) is endemic in Liaoning Province. Both Seoul and Hantaan virus are circulating in rodents, and epidemic outbreaks and sporadic cases have been recorded every year since the disease was recognized.

What is added by this report?

The epidemic trend of HFRS over the past 20 years (1999-2018) in Liaoning was analyzed, which showed both regional complexity and consistence with the epidemic in China. Genetic and antigenic stability of the circulating hantavirus were demonstrated, which suggested the effectiveness of the approved inactivated vaccine currently used in China.

What are the implications for public health practice?

Precise risk-based strategic practices that are integrated and regional are required for further improvement of the prevention and control of HFRS.

Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020.

Grants and funding

This work was supported by National Mega-Projects for Infectious Disease (2016ZX10004222-002, 2018ZX10711001), and National Key Research and Development Program of China (2016YFD0500303).