The Association of Age at Diagnosis of Hypertension With Brain Structure and Incident Dementia in the UK Biobank

Hypertension. 2021 Nov;78(5):1463-1474. doi: 10.1161/HYPERTENSIONAHA.121.17608. Epub 2021 Oct 4.

Xianwen Shang^{1

2}, Edward Hill^{3

4}, Zhuoting Zhu^{1

2}, Jiahao Liu⁵, B Zongyuan Ge⁶, Wei Wang⁷, Mingguang He^{1

7

8}

¹ Guangdong Eye Institute, Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (X.S., Z.Z., M.H.).
² Guangdong Cardiovsacular Institute, Guangzhou, China (X.S., Z.Z.).
³ Department of Medicine (Royal Melbourne Hospital) (E.H.), University of Melbourne, VIC, Australia.
⁴ Wicking Dementia Research and Education Centre, University of Tasmania, Australia (E.H.).
⁵ Melbourne School of Population and Global Health (J.L.), University of Melbourne, VIC, Australia.
⁶ Monash e-Research Center, Faculty of Engineering, Airdoc Research, Nvidia AI Technology Research Center, Monash University, Melbourne, VIC, Australia (Z.G.).
⁷ State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China (W.W., M.H.).
⁸ Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia (M.H.).

Abstract

[Figure: see text].

Keywords: adult; dementia; hypertension; magnetic resonance imaging; propensity score.