Aims: Based on the complex pathological environment of perioperative stroke, the development of targeted therapeutic strategies is important to control the development of perioperative stroke.
Discussions: Recently, great progress has been made in nanotechnology, and nanodrug delivery systems have been developed for the treatment of ischemic stroke.
Conclusion: In this review, the pathological processes and mechanisms of ischemic stroke during perioperative stroke onset were systematically sorted. As a potential treatment strategy for perioperative stroke, the review also summarizes the multifunctional nanodelivery systems based on ischemic stroke, thus providing insight into the nanotherapeutic strategies for perioperative stroke.
Keywords: anti-inflammatory; antioxidant; nanodelivery system; neuronal regeneration; perioperative stroke; thrombolysis.
© 2022 The Authors. CNS Neuroscience & Therapeutics published by John Wiley & Sons Ltd.