First case of Zika virus infection during an outbreak of chikungunya in a rural region of Maharashtra state, India

Yogesh K Gurav; Kalichamy Alagarasu; Pragya D Yadav; Gajanan Sapkal; Mangesh Gokhale; Deepti Parashar; Ujwala Jadhav; Minal Bote; Mahadeo Kakade; Dimpal Nyayanit; Abhinendra Kumar; Gururaj Rao Deshpande; Sarah Cherian; Pradip S Awate; Priya Abraham

doi:10.1093/trstmh/trac022

First case of Zika virus infection during an outbreak of chikungunya in a rural region of Maharashtra state, India

Trans R Soc Trop Med Hyg. 2022 Oct 2;116(10):974-977. doi: 10.1093/trstmh/trac022.

Authors

Affiliations

¹ ICMR-National Institute of Virology, Pune, Maharashtra, India.
² Taluka Health Officer, Purandar, District Pune, Maharashtra, India.
³ State Surveillance Officer, Integrated Diseases Surveillance Programme, Maharashtra, India.

PMID: 35415761
DOI: 10.1093/trstmh/trac022

Abstract

Background: In July 2021, an outbreak of chikungunya virus (CHIKV) was reported in a rural region of Maharashtra state, India.

Methods: Serum samples of symptomatic cases (n=33) were screened for dengue virus (DENV), CHIKV and Zika virus (ZIKV) by molecular and serological assays.

Results: The first case of ZIKV infection from Maharashtra was detected and confirmed by molecular and serological assays. Complete genome sequencing revealed that the ZIKV sequence belongs to the Asian genotype and had a closer homology with pre-epidemic strains present before 2007.

Conclusions: ZIKV surveillance needs to be strengthened in the regions experiencing dengue and chikungunya outbreaks.

Keywords: India; Zika virus; chikungunya virus; dengue virus; outbreaks; rural population.

Publication types

Case Reports

MeSH terms

Chikungunya Fever* / epidemiology
Chikungunya virus* / genetics
Dengue Virus* / genetics
Dengue* / epidemiology
Disease Outbreaks
Humans
India / epidemiology
Zika Virus Infection* / diagnosis
Zika Virus Infection* / epidemiology
Zika Virus* / genetics