Is Glucagon Administration Compatible With FDG PET/MRI?

Clin Nucl Med. 2022 Aug 1;47(8):730-731. doi: 10.1097/RLU.0000000000004225. Epub 2022 Apr 15.

Abstract

Digestive peristalsis generates many artifacts that limit the abdominal and pelvic MRI interpretation. Apart from the hypoglycemia treatment in patients with diabetes, glucagon analog is also indicated for the digestive peristalsis reduction to reduce MRI artifacts. However, its use in PET/MRI is not described, given the risk of interaction with the metabolism of FDG. To assess the importance of this interaction on the FDG PET images, we report FDG PET/MRI images obtained with and without glucagon analog injection.

MeSH terms

  • Artifacts
  • Fluorodeoxyglucose F18*
  • Glucagon*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Positron-Emission Tomography / methods

Substances

  • Fluorodeoxyglucose F18
  • Glucagon