The brain-from neurodevelopment to neurodegeneration

FEBS J. 2022 Apr;289(8):2010-2012. doi: 10.1111/febs.16436.

Abstract

The brain is the organ that orchestrates the whole body. To do so, neurons and glia in different brain regions have evolved to be highly specialized and are regulated by diverse receptors and neuro- and gliotransmitters. Some of the features of the brain, including a protective brain-blood barrier, high-energy demand, and electrical activity, mean that neurons and astrocytes are uniquely diverse components of tissue that vary greatly even across brain regions. This Special Issue features 19 review articles that cover different aspects of the broad field of neuroscience-from neurodevelopment, physiology and memory formation to the mechanisms underlying the development of neurodegenerative diseases.

Keywords: astrocyte; brain; neurodegeneration; neurodevelopment; neuron.

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Astrocytes* / physiology
  • Brain
  • Humans
  • Neurodegenerative Diseases*
  • Neurons / physiology