Novel case of primary intracranial solitary plasmacytoma presenting with significant intratumoral hemorrhage

Daisuke Sato; Shunsaku Takayanagi; Hirokazu Takami; Tetsuaki Iwamoto; Masashi Nomura; Shohei Nambu; Masako Ikemura; Shota Tanaka; Nobuhito Saito

doi:10.25259/SNI_66_2022

Novel case of primary intracranial solitary plasmacytoma presenting with significant intratumoral hemorrhage

Surg Neurol Int. 2022 Apr 22:13:157. doi: 10.25259/SNI_66_2022. eCollection 2022.

Authors

Daisuke Sato¹, Shunsaku Takayanagi¹, Hirokazu Takami¹, Tetsuaki Iwamoto², Masashi Nomura¹, Shohei Nambu¹, Masako Ikemura³, Shota Tanaka¹, Nobuhito Saito¹

Affiliations

¹ Department of Neurosurgery, The University of Tokyo Hospital, Tokyo.
² Department of Neurosurgery, Higashi Yokohama Hospital, Yokohama.
³ Department of Pathology, The University of Tokyo Hospital, Tokyo, Japan.

Abstract

Background: Solitary plasmacytoma is a localized lesion comprising monoclonal neoplastic proliferation of plasma cells. This disease is rarely encountered and few reports have described primary intracranial solitary plasmacytoma (PISP).

Case description: We report a case of PISP that presented initially as status epilepticus and exhibited massive intratumoral hemorrhage at the subcortical area. To the best of our knowledge, this is the first recorded presentation of this pathology in this manner. Following evacuation of the hematoma and decompressive craniectomy, the patient underwent radiation therapy and showed no sign of tumor recurrence at 3 years after diagnosis.

Conclusion: This case reveals that PISP can present as subcortical intraparenchymal hemorrhage. It should be emphasized that the precise diagnosis of this disease is of utmost importance, because solitary plasmacytoma without a background of multiple myeloma responds well to radiation therapy.

Keywords: Decompressive craniectomy; Intratumoral hemorrhage; Primary intracranial solitary plasmacytoma; Radiotherapy.

Publication types

Case Reports