First-in-human phase 1 trial of hemoglobin vesicles as artificial red blood cells developed for use as a transfusion alternative

Affiliations

• ¹ Department of Pediatrics, Asahikawa Medical University, Asahikawa, Japan.
• ² Clinical Research and Medical Innovation Center, Hokkaido University Hospital, Sapporo, Japan.
• ³ Clinical Research Support Center, Asahikawa Medical University, Asahikawa, Japan.
• ⁴ Department of Chemistry, Nara Medical University, Kashihara, Japan.
• ⁵ Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan.
• ⁶ Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan.
• ⁷ Cell Processing Center, Nara Medical University Hospital, Kashihara, Japan.