Neonatal nutritional risk and pulmonary function

Medicine (Baltimore). 2022 Aug 12;101(32):e29662. doi: 10.1097/MD.0000000000029662.

Abstract

Introduction: The neonatal period is a critical initial stage of postnatal lung development and maturation. This study aimed to investigate the effects of the nutritional status on pulmonary function in late preterm and full-term neonates.

Methods: A total of 172 newborns were included in the study. Nutritional risk screening, weight measurement, assessment of albumin and caloric intake, and a pulmonary function examination were conducted on the 7th day after birth.

Results: There was a significant correlation between the nutritional risk and changes in body weight. Tidal volume (VT), minute ventilation (MV), VT per kg body weight (VT/kg), and MV per kg body weight (MV/kg) in the low nutritional risk group were significantly higher than those in the medium nutritional risk group (all P < .05). Albumin and caloric intake in the low nutritional risk group were significantly higher than those in the medium nutritional risk group (both P < .01). VT, VT/kg, MV, and MV/kg in the weight loss group were lower than those in the no weight loss group (all P < .05).

Conclusions: Changes in neonatal weight mainly affect lung volume (VT, VT/kg, MV, and MV/kg), suggesting that an improvement in the neonatal nutritional status is important for the development of lung volume.

MeSH terms

  • Albumins
  • Body Weight
  • Humans
  • Infant, Newborn
  • Lung*
  • Respiration, Artificial*
  • Tidal Volume

Substances

  • Albumins