Giant congenital melanocytic naevus with a novel CUX1-BRAF fusion mutation treated with trametinib

Br J Dermatol. 2022 Dec;187(6):1052-1054. doi: 10.1111/bjd.21851. Epub 2022 Sep 16.
No abstract available

Publication types

  • Letter

MeSH terms

  • Homeodomain Proteins / genetics
  • Humans
  • Mutation / genetics
  • Nevus, Pigmented* / congenital
  • Nevus, Pigmented* / drug therapy
  • Nevus, Pigmented* / genetics
  • Proto-Oncogene Proteins B-raf / genetics
  • Repressor Proteins / genetics
  • Skin Neoplasms* / congenital
  • Skin Neoplasms* / drug therapy
  • Skin Neoplasms* / genetics
  • Transcription Factors / genetics

Substances

  • trametinib
  • Proto-Oncogene Proteins B-raf
  • BRAF protein, human
  • CUX1 protein, human
  • Repressor Proteins
  • Transcription Factors
  • Homeodomain Proteins

Supplementary concepts

  • Melanocytic nevus syndrome, congenital