Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions
Blood
.
2023 Feb 16;141(7):800-805.
doi: 10.1182/blood.2022017874.
Authors
Georgina L Ryland
1
2
3
,
Masayuki Umeda
4
,
Linda Holmfeldt
5
6
,
Sören Lehmann
7
,
Morten Krogh Herlin
8
9
,
Jing Ma
4
,
Mahsa Khanlari
4
,
Jeffrey E Rubnitz
10
,
Rhonda E Ries
11
,
Hansen J Kosasih
12
,
Paul G Ekert
3
12
13
14
15
,
Hwee Ngee Goh
1
,
Ing S Tiong
1
,
Sean M Grimmond
2
,
Claudia Haferlach
16
,
Ryan B Day
17
,
Timothy J Ley
17
,
Soheil Meshinchi
11
,
Xiaotu Ma
18
,
Piers Blombery
1
3
19
,
Jeffery M Klco
4
Affiliations
1
Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
2
Centre for Cancer Research, University of Melbourne, Parkville, VIC, Australia.
3
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.
4
Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
5
Department of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
6
The Beijer Laboratory, Uppsala, Sweden.
7
Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.
8
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
9
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.
10
Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
11
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
12
Murdoch Children's Research Institute, Parkville, VIC, Australia.
13
Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.
14
Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.
15
Discipline of Paediatrics and Child Health, School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.
16
Munich Leukemia Laboratory, Munich, Germany.
17
Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
18
Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
19
Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.
PMID:
36179268
PMCID:
PMC10273080
DOI:
10.1182/blood.2022017874
No abstract available
Publication types
Comment
MeSH terms
Core Binding Factor beta Subunit
Humans
Leukemia, Myeloid, Acute* / genetics
Oncogene Proteins, Fusion
Substances
Oncogene Proteins, Fusion
Core Binding Factor beta Subunit
CBFB protein, human
Grants and funding
P30 CA021765/CA/NCI NIH HHS/United States
R35 CA197561/CA/NCI NIH HHS/United States