A case series of eosinophilic myocarditis: different faces of the same coin

Bethlehem Mengesha; Karen Meir; Alexander Gural; Rabea Asleh

doi:10.1093/ehjcr/ytac388

A case series of eosinophilic myocarditis: different faces of the same coin

Eur Heart J Case Rep. 2022 Sep 16;6(9):ytac388. doi: 10.1093/ehjcr/ytac388. eCollection 2022 Sep.

Authors

Bethlehem Mengesha¹, Karen Meir², Alexander Gural³, Rabea Asleh¹

Affiliations

¹ Heart Institute, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
² Department of Pathology. Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
³ Department of Hematology. Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.

Abstract

Background: Eosinophilic myocarditis (EM) is a rare form of myocarditis with various aetiologies and dire consequences if not diagnosed and treated expeditiously.

Case summary: We report three cases of EM at different stages of the disease with differing clinical manifestations. We highlight the diagnostic workup including the role of multimodality imaging and endomyocardial biopsy (EMB), and the treatment strategies.

Discussion: EM is an underdiagnosed and potentially life-threatening disease. Therefore, a high clinical suspicion for EM should arise when patients with signs and symptoms of cardiovascular disease develop hypereosinophilia or vice versa. Early identification of this condition using multimodality imaging and EMB is of paramount importance as the disease may progress to the irreversible late fibrotic stage if treatment is delayed.

Keywords: Case series; Eosinophilic myocarditis; Heart failure; Hypereosinophilia.

Publication types

Case Reports