Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease - China's Studies

Kang Xiao; Qi Shi; Cao Chen; Wei Zhou; Chen Gao; Liping Gao; Jun Han; Jichun Wang; Xiaoping Dong

doi:10.46234/ccdcw2022.152

Establishment of a Special Platform for the Research of Prion and the Diagnosis of Human Prion Disease - China's Studies

China CDC Wkly. 2022 Aug 19;4(33):729-734. doi: 10.46234/ccdcw2022.152.

Authors

Kang Xiao¹, Qi Shi^{1

2}, Cao Chen^{1

3}, Wei Zhou¹, Chen Gao¹, Liping Gao¹, Jun Han¹, Jichun Wang^{1

4}, Xiaoping Dong^{1

2

3

5}

Affiliations

¹ State Key Laboratory for Infectious Disease Prevention and Control, NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
² China Academy of Chinese Medical Sciences, Beijing, China.
³ Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan City, Hubei Province, China.
⁴ Division of Science and Technology, Chinese Center for Disease Control and Prevention, Beijing, China.
⁵ Shanghai Institute of Infectious Disease and Biosafety, Shanghai Municipality, China.

Abstract

The studies of prions and prion disease usually need many special platforms and techniques that differ from those for classical microbes. Search of new biomarkers and establishment of new methods for the diagnosis of human prion diseases are priorities in the field of prion study.

Keywords: PMCA; Prion; RT-QuIC.

Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022.

Publication types

Review

Grants and funding

Supported by SKLID Development Grant (2021SKLID506, 2019SKLID501, 2019SKLID603, 2021SKLID101), and National Natural Science Foundation of China (81572048)