Spontaneous regression of colloid cyst on the third ventricle: a case report with the review of the literature

BMC Neurol. 2022 Oct 29;22(1):397. doi: 10.1186/s12883-022-02933-6.

Abstract

Background: Colloid cyst (CC) is a rare and benign cyst found in the third ventricle near the foramen of Monro. Although the role of surgical resection is well established in symptomatic large-sized CC, it remains debatable whether surgical removal of CC with no symptoms or minimal symptoms is necessary.

Case presentation: A 49-year-old male patient visited our institute for incidentally detected intracranial mass. MRI demonstrated typical, 12 mm-sized CC located in the third ventricle. It was noticed that the cyst spontaneously decreased in size from 12 mm to 4 mm on MRI at 18 months after the first visit.

Conclusion: Although spontaneous regression is a very rare phenomenon in CC, regular imaging study and frequent neurologic examination can be an alternative option for well-selected, asymptomatic cases.

Keywords: Colloid cyst; Natural history; Spontaneous regression; Third ventricle.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Colloid Cysts* / diagnostic imaging
  • Colloid Cysts* / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurologic Examination
  • Third Ventricle* / diagnostic imaging
  • Third Ventricle* / surgery