Pevonedistat with azacitidine in older patients with TP53-mutated AML: a phase 2 study with laboratory correlates

Blood Adv. 2023 Jun 13;7(11):2360-2363. doi: 10.1182/bloodadvances.2022008625.
No abstract available

Publication types

  • Clinical Trial, Phase II
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Azacitidine* / therapeutic use
  • Cyclopentanes
  • Humans
  • Leukemia, Myeloid, Acute* / drug therapy
  • Leukemia, Myeloid, Acute* / genetics
  • Pyrimidines
  • Tumor Suppressor Protein p53 / genetics

Substances

  • Azacitidine
  • pevonedistat
  • Cyclopentanes
  • Pyrimidines
  • TP53 protein, human
  • Tumor Suppressor Protein p53

Associated data

  • ClinicalTrials.gov/NCT03013998