Nucleic Acid Aptamers for Pesticides, Toxins, and Biomarkers in Agriculture

Rongping Hu; Jun Shi; Cheng Tian; Xiaojuan Chen; Hua Zuo

doi:10.1002/cplu.202200230

Nucleic Acid Aptamers for Pesticides, Toxins, and Biomarkers in Agriculture

Chempluschem. 2022 Nov;87(11):e202200230. doi: 10.1002/cplu.202200230.

Authors

Rongping Hu¹, Jun Shi², Cheng Tian³, Xiaojuan Chen¹, Hua Zuo³

Affiliations

¹ Sichuan Institute of Edible Fungi, Institute of Plant Protection, Sichuan Academy of Agricultural Sciences, Chengdu, Sichuan, 610066, P. R. China.
² Mianyang Academy of Agricultural Sciences, Crop Characteristic Resources Creation, and Utilization Key Laboratory of Sichuan Province, Mianyang, Sichuan, 621023 (P. R., China.
³ Key Laboratory of Luminescence Analysis, and Molecular Sensing (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, P. R. China.

PMID: 36410759
DOI: 10.1002/cplu.202200230

Abstract

Nucleic acid aptamers are short single-stranded DNA/RNA (ssDNA/RNA) oligonucleotides that can selectively bind to the targets. They are widely used in medicine, biosensing, and diagnostic assay. They have also been identified and extensively used for various targets in agriculture. In this review we summarize the progress of nucleic acid aptamers on pesticides (herbicides, insecticides, and fungicides), toxins, specific biomarkers of crops, and plant growth regulators in agricultural field in recent years. The basic process of aptamer selection, the already identified DNA/RNA aptamers and the aptasensors are discussed. We also discuss the future perspectives and the challenges for aptamer development in agriculture.

Keywords: SELEX; agriculture; aptamers; aptasensor; nucleic acids.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Agriculture
Biomarkers
Nucleic Acids*
Oligonucleotides
Pesticides*
RNA

Substances

Pesticides
Nucleic Acids
Oligonucleotides
Biomarkers
RNA