Severe thrombocytopenia and anemia as an initial presentation of breast cancer: A case report

Ryota Otsubo; Hiroshi Yano; Hidehiro Itonaga; Keisuke Iwasaki; Keiko Segawa; Takeshi Nagayasu

doi:10.1002/ccr3.6762

Severe thrombocytopenia and anemia as an initial presentation of breast cancer: A case report

Clin Case Rep. 2022 Dec 20;10(12):e6762. doi: 10.1002/ccr3.6762. eCollection 2022 Dec.

Authors

Ryota Otsubo^{1

2}, Hiroshi Yano², Hidehiro Itonaga³, Keisuke Iwasaki⁴, Keiko Segawa⁵, Takeshi Nagayasu¹

Affiliations

¹ Department of Surgical Oncology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
² Department of Breast Surgery, Sasebo City General Hospital Nagasaki Japan.
³ Department of Hematology, Sasebo City General Hospital Nagasaki Japan.
⁴ Department of Pathology, Sasebo City General Hospital Nagasaki Japan.
⁵ Department of Radiology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.

Abstract

Breast cancer patients with bone marrow metastasis (BMM) having profound thrombocytopenia and anemia are rare and there is no definitive treatment guideline. We present a case of successful initial treatment with anti-disseminated intravascular coagulation therapy and endocrine therapy, followed by chemotherapy to avoid deterioration of severe thrombocytopenia and anemia.

Keywords: anemia; bone marrow metastasis; breast cancer; chemotherapy; endocrine therapy; thrombocytopenia.

Publication types

Case Reports