Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study

BMJ Open. 2022 Jun 3;12(6):e054682. doi: 10.1136/bmjopen-2021-054682.

Abstract

Background: Dyslipidaemia is different among patients with hypertension in different populations. The serum lipid profiles among Hakka patients with hypertension in southern China are still unclear.

Methods: 35 448 patients with hypertension were enrolled in this study from January 2016 to October 2020, and their serum lipids were analysed.

Results: Low high-density lipoprotein-cholesterol (HDL-C) (29.9%) accounted for the highest proportion in dyslipidaemia, followed by high triglyceride (TG) (20.7%), high total cholesterol (TC) (14.0%) and high low-density lipoprotein-cholesterol (LDL-C) (7.9%) in all subjects. The largest proportion of dyslipidaemia types was independent low HDL-C (12.7%). The proportion of low HDL-C was 15.5% in non-elderly men, 6.4% in non-elderly women, 16.7% in elderly men and 8.5% in elderly women, respectively. The largest proportion of dyslipidaemia types was independent high TG in non-elderly female patients (13.7%) and elderly patients (8.9%). The results showed that higher LDL-C, TC and TG levels in non-elderly patients than elderly patients. TG, TC and LDL-C levels decreasing with the increasing age, the differences were statistically significant. The levels of TG, TC, HDL-C and LDL-C in women were higher than in men among various age groups. Homocysteine level was increasing with increasing age.

Conclusions: Serum lipid levels varied in different groups according to age and sex in patients with hypertension. Dyslipidaemia is more common in non-elderly patients than elderly. TG, TC and LDL-C levels were higher in female patients than male.

Keywords: Coronary heart disease; Hypertension; Lipid disorders.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cholesterol
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Dyslipidemias* / epidemiology
  • Female
  • Humans
  • Hypertension* / epidemiology
  • Lipids
  • Male
  • Middle Aged
  • Retrospective Studies
  • Triglycerides

Substances

  • Cholesterol, LDL
  • Lipids
  • Cholesterol
  • Triglycerides
  • Cholesterol, HDL