Animal host range of mpox virus

Kangxin Li; Yupei Yuan; Lu Jiang; Yuwen Liu; Yihan Liu; Leiliang Zhang

doi:10.1002/jmv.28513

Animal host range of mpox virus

J Med Virol. 2023 Feb;95(2):e28513. doi: 10.1002/jmv.28513.

Authors

Kangxin Li^{1

2

3}, Yupei Yuan², Lu Jiang², Yuwen Liu², Yihan Liu², Leiliang Zhang^{1

2

3}

Affiliations

¹ Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
² Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
³ Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.

PMID: 36661039
DOI: 10.1002/jmv.28513

Abstract

Mpox is caused by the mpox virus, which belongs to the Orthopoxvirus genus and Poxviridae family. Animal hosts, such as African rodents, mice, prairie dogs, and non-human primates, play important roles in the development and transmission of outbreaks. Laboratory animal infection experiments have demonstrated that some animals are susceptible to mpox virus. This review summarizes the current progress on the animal hosts for mpox virus. The surveillance of mpox virus in animal hosts will provide important insights into virus tracing, analysis of mutation evolutionary patterns, transmission mechanisms, and development of control measures.

Keywords: African rodents; host range; mpox; non-human primates; orthopoxvirus.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Host Specificity
Mice
Monkeypox virus*
Mpox (monkeypox)* / veterinary
Primates / virology
Sciuridae / virology