Intraoperative Kounis Syndrome and Fixation Errors: A Case Report

A A Pract. 2023 Mar 20;17(3):e01672. doi: 10.1213/XAA.0000000000001672. eCollection 2023 Mar 1.

Abstract

Postinduction hypotension, though frequently due to anesthetic medications, has a variety of causes. We present a case of presumed intraoperative Kounis syndrome, or anaphylaxis-induced coronary vasospasm, in which the patient's perioperative course was initially attributed to anesthesia-induced hypotension and iatrogenic rebound hypertension leading to Takotsubo cardiomyopathy. A second anesthetic event with immediate recurrence of hypotension after the patient received levetiracetam appears to confirm the diagnosis of Kounis syndrome. In this report, we discuss the fixation error that led to this patient's original misdiagnosis.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis* / chemically induced
  • Coronary Vasospasm* / chemically induced
  • Coronary Vasospasm* / diagnosis
  • Humans
  • Hypotension* / chemically induced
  • Hypotension* / complications
  • Kounis Syndrome* / diagnosis
  • Kounis Syndrome* / etiology