Management of acute pericarditis

Curr Opin Cardiol. 2023 Jul 1;38(4):364-368. doi: 10.1097/HCO.0000000000001056. Epub 2023 Apr 10.

Abstract

Purpose of review: Provide an update on current management and most recent evidence in the treatment of pediatric pericarditis.

Recent findings: While treatment of acute pericarditis has not significantly changed over the last decade, management of recurrent acute pericarditis, with increased attention to autoinflammation as a causal mechanism, has evolved substantially. This includes clinical trial evidence that newer medications targeting interleukin-1 receptors are effective in recurrent forms of pericarditis. In addition, advanced imaging utilizing cardiac magnetic resonance has emerged as a particularly effective way to detect ongoing pericardial inflammation in support of more difficult-to-treat patients.

Summary: Recent advances in acute and recurrent pericarditis management have allowed for a more tailored approach to the individual patient. Yet, unresolved questions require further research.

Publication types

  • Review

MeSH terms

  • Child
  • Humans
  • Inflammation
  • Magnetic Resonance Imaging
  • Pericarditis* / diagnosis
  • Pericarditis* / drug therapy
  • Pericardium