Antibody-cytokine fusion breathes new life into glioblastoma therapy

Sci Transl Med. 2023 May 24;15(697):eadh7674. doi: 10.1126/scitranslmed.adh7674. Epub 2023 May 24.

Abstract

An antibody-cytokine fusion molecule combined with chemotherapy induces tumor regression in mice and patients with recurrent glioblastoma by boosting antitumor immunity (Look et al.).

Publication types

  • Review

MeSH terms

  • Animals
  • Antibodies
  • Cytokines*
  • Glioblastoma* / drug therapy
  • Mice

Substances

  • Cytokines
  • Antibodies