Mapping Non-Coding RNAs in Space and Time: Another Weapon to Dissect Intra-Tumor Heterogeneity in Cancer Progression

Mario Cioce; Andrea Marra; Daniela Rutigliano; Vito Michele Fazio

doi:10.3390/cancers15123181

Mapping Non-Coding RNAs in Space and Time: Another Weapon to Dissect Intra-Tumor Heterogeneity in Cancer Progression

Cancers (Basel). 2023 Jun 14;15(12):3181. doi: 10.3390/cancers15123181.

Authors

Mario Cioce^{1

2}, Andrea Marra^{1

2}, Daniela Rutigliano¹, Vito Michele Fazio^{1

2}

Affiliations

¹ Laboratory of Molecular Medicine and Biotechnology, Department of Medicine, University Campus Bio-Medico of Rome, 00128 Rome, Italy.
² Institute of Translational Pharmacology, National Research Council of Italy (CNR), 00133 Rome, Italy.

Abstract

It is increasingly clear that Intratumor heterogeneity (ITH) fuels tumor evolution, matching the concept of cancer as a heterogeneous ecosystem of spatially and temporally modulated cell subpopulations, which exploits dynamic strategies to hijack local and systemic resources and tissue(s) space [...].

Publication types

Editorial