Patterns of immune equilibrium and escape in indolent and progressing tumors

Abhinav Pandey; Maximilian Linxweiler; Fengshen Kuo; Jennifer L Marti; Benjamin Roman; Behfar Ehdaie; Joris L Vos; Luc G T Morris

doi:10.1016/j.ccell.2023.06.003

Patterns of immune equilibrium and escape in indolent and progressing tumors

Cancer Cell. 2023 Aug 14;41(8):1389-1391. doi: 10.1016/j.ccell.2023.06.003. Epub 2023 Jul 6.

Authors

Abhinav Pandey¹, Maximilian Linxweiler², Fengshen Kuo¹, Jennifer L Marti³, Benjamin Roman¹, Behfar Ehdaie¹, Joris L Vos¹, Luc G T Morris⁴

Affiliations

¹ Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
² Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Otorhinolaryngology, Saarland University, Homburg, Germany.
³ Breast Cancer Center, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁴ Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: morrisl@mskcc.org.

PMID: 37419120
PMCID: PMC10849086 (available on 2024-08-14)
DOI: 10.1016/j.ccell.2023.06.003

Abstract

By comparing indolent/slowly progressing with aggressive/rapidly progressing tumor types, Pandey et al. identify human evidence of immune equilibrium in indolent tumors and immune escape in progressing tumors, suggesting a link between these mechanisms and the epidemiologic phenomenon of overdiagnosis.

Patterns of immune equilibrium and escape in indolent and progressing tumors

Authors

Affiliations

Abstract

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