Effect of two antibacterial mouth sprays and dentifrices on dental plaque and gingivitis in beagle dogs

J Dent Res. 1979 May;58(5):1471-7. doi: 10.1177/00220345790580050801.

Abstract

Plaque inhibition by dilute mouth sprays and dentrifrices containing benzethonium chloride and chlorhexidine gluconate was compared in beagle dogs. Agents with chlorhexidine gluconate produced less plaque than their benzethonium chloride or placebo counterparts, but the differences were not significant when compared to mean control scores registered during interexperimental recovery periods.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Aerosols
  • Animals
  • Benzethonium / administration & dosage*
  • Benzethonium / therapeutic use
  • Biguanides / administration & dosage*
  • Chlorhexidine / administration & dosage*
  • Chlorhexidine / therapeutic use
  • Clinical Trials as Topic
  • Dental Plaque / prevention & control*
  • Dentifrices / therapeutic use*
  • Dogs
  • Double-Blind Method
  • Gingival Crevicular Fluid / analysis
  • Gingivitis / prevention & control*
  • Male
  • Placebos
  • Quaternary Ammonium Compounds / administration & dosage*

Substances

  • Aerosols
  • Biguanides
  • Dentifrices
  • Placebos
  • Quaternary Ammonium Compounds
  • Benzethonium
  • Chlorhexidine