Sleep Deficiency and Cardiometabolic Disease

Roo Killick; Lachlan Stranks; Camilla M Hoyos

doi:10.1016/j.jsmc.2023.05.012

Sleep Deficiency and Cardiometabolic Disease

Sleep Med Clin. 2023 Sep;18(3):331-347. doi: 10.1016/j.jsmc.2023.05.012.

Authors

Roo Killick¹, Lachlan Stranks², Camilla M Hoyos³

Affiliations

¹ Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia.
² Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia; The University of Adelaide, Faculty of Health and Medical Sciences, Adelaide, Australia.
³ Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia; The University of Sydney, Faculty of Science, School of Psychology and Brain and Mind Centre, Sydney, Australia. Electronic address: camilla.hoyos@sydney.edu.au.

PMID: 37532373
DOI: 10.1016/j.jsmc.2023.05.012

Abstract

Epidemiologic studies have demonstrated that short sleep duration is associated with an increased risk of cardio-metabolic health outcomes including cardiovascular disease mortality, coronary heart disease, type 2 diabetes mellitus, hypertension, and metabolic syndrome. Experimental sleep restriction studies have sought to explain these findings. This review describes the main evidence of these associations and possible mechanisms explaining them. Whether sleep extension reverses these now widely acknowledged adverse health effects and the feasibility of implementing such strategies on a public health level is discussed.

Keywords: Cardiometabolic outcomes; Cardiovascular disease; Metabolic health; Sleep deprivation; Sleep restriction.

Publication types

Review

MeSH terms

Cardiovascular Diseases* / epidemiology
Diabetes Mellitus, Type 2* / complications
Diabetes Mellitus, Type 2* / epidemiology
Humans
Hypertension*
Risk Factors
Sleep