Catching proteins for degradation

Science. 2023 Aug 25;381(6660):834-835. doi: 10.1126/science.adj8230. Epub 2023 Aug 24.

Abstract

Aubiquitin-independent pathway targets nuclear proteins to the proteasome.

MeSH terms

  • Animals
  • Cytoplasm
  • Genes, Immediate-Early*
  • Humans
  • Mice
  • Nuclear Proteins* / chemistry
  • Nuclear Proteins* / metabolism
  • Proteasome Endopeptidase Complex* / chemistry
  • Proteasome Endopeptidase Complex* / metabolism
  • Proteolysis*

Substances

  • Nuclear Proteins
  • Proteasome Endopeptidase Complex
  • midnolin