Human papillomavirus type 94-associated flat warts and review of reported cases

J Dermatol. 2024 Jan;51(1):95-97. doi: 10.1111/1346-8138.16962. Epub 2023 Sep 12.

Abstract

To date, 10 types of human papillomavirus have been identified that cause flat warts, including human papillomavirus type 3, which belongs to species group 2 of the genus alpha papillomavirus. Among these 10 types, human papillomavirus type 94 is most closely related to human papillomavirus type 10, sharing 86% homology. In this study, we conducted polymerase chain reaction analysis with sequencing on samples obtained from cutaneous lesions located on the face and lower legs of an individual, revealing the presence of human papillomavirus type 94. Dermatoscopic findings revealed numerous dotted vessels within one group of macular brown lesions located on the lower leg, which contributed to the diagnosis of flat warts. An online search revealed that human papillomavirus type 94 has previously been detected in various skin diseases, and we provide a review of prior reports.

Keywords: dermoscopy; flat warts; human papillomavirus; review of reported cases; type 94.

Publication types

  • Review

MeSH terms

  • DNA, Viral / genetics
  • Human Papillomavirus Viruses
  • Humans
  • Papillomaviridae / genetics
  • Papillomavirus Infections* / diagnosis
  • Warts* / pathology

Substances

  • DNA, Viral