Developmental biology: A hole in the matrix

Douglas S Portman; Carlos A Díaz-Balzac

doi:10.1016/j.cub.2023.08.082

Developmental biology: A hole in the matrix

Curr Biol. 2023 Oct 9;33(19):R1016-R1018. doi: 10.1016/j.cub.2023.08.082.

Authors

Douglas S Portman¹, Carlos A Díaz-Balzac²

Affiliations

¹ Department of Biomedical Genetics, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA; Department of Neuroscience, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA; Department of Biology, University of Rochester, 402 Hutchison Hall, Rochester, NY 14627, USA. Electronic address: douglas.portman@rochester.edu.
² Department of Biomedical Genetics, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA; Department of Medicine, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.

PMID: 37816322
DOI: 10.1016/j.cub.2023.08.082

Abstract

Neurons must access the environment to gather information, but this exposure must be carefully managed. New work finds that glial cells, the non-neuronal component of the nervous system, control environmental access by stage- and sex-specific patterning of the extracellular matrix.

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MeSH terms

Developmental Biology
Extracellular Matrix / physiology
Female
Humans
Male
Neuroglia* / physiology
Neurons* / physiology