Rethinking about acupuncture intervention opportunity based on dynamic perspective of inflammatory response

Zhen Ci Yan Jiu. 2023 Oct 25;48(10):1062-1068. doi: 10.13702/j.1000-0607.20220682.
[Article in English, Chinese]

Abstract

Acupuncture and moxibustion therapies are widely used in the field of anti-inflammation, but the dynamic characteristics of inflammatory response with time in the modern biological mechanism research has been ignored to some extent. Therefore, the body surface intervention system represented by acupuncture-moxibustion urgently needs to rebuild the research perspective oriented to the complex immune regulation model, and then to explore the opportunity of acupuncture-moxibustion anti-inflammatory intervention according to the dynamic change process of inflammatory response. Through comparative analysis on the ancient and modern acupuncture-moxibustion immune regulation, and starting from the construction of clinical body surface intervention system, we propose that grasping the appropriate "intervention opportunity" is an important entry point that cannot be ignored to effectively "pry" inflammatory response.

针灸在抗炎领域应用广泛且疗效确切,但其抗炎效应的现代生物学机制研究在某种程度上忽略了炎性反应具有随时间变化的动态性特征。因此,以针灸为代表的体表干预体系亟需重建面向复杂免疫调控模式的研究视角,立足炎性反应的动态变化过程,继而探索针灸抗炎的介入时机。本文拟通过古今针灸免疫调控的对比分析,从临床体表干预体系的构建着手,提出对针灸干预体系中恰当“介入时机”的把握是针灸等体表干预方式有效“撬动”炎性反应不可忽视的重要切入点与靶点。.

Keywords: Acupuncture and moxibustion; Dynamic change; Inflammation response; Timing of intervention.

MeSH terms

  • Acupuncture Therapy*
  • Hand Strength
  • Moxibustion*