Anxiety, Depression, and Coping Strategies during Chemotherapy Treatment: A Comparison of Older and Younger Adults with Advanced Cancer in Brazil

Cancer Invest. 2023 Oct;41(9):781-788. doi: 10.1080/07357907.2023.2274033. Epub 2023 Nov 17.

Abstract

We sought to examine differences in anxiety, depression and coping strategies among younger (<64-year old) and older (≥65-year old) patients. Patients were assessed at baseline (T1), mid-point (T2) and on the last day of treatment (T3) using the Hospital Anxiety and Depression Scale and the Ways of Coping. A linear mixed modeling approach was used. The study included 200 patients (gender: 70% women; diagnosis: 30% breast, 22% hematological, 18% gastrointestinal; disease stage: 60% advanced). Older patients who used an emotion-focused coping strategy had a greater decrease in anxiety at T3 compared to those that used problem-focused coping (p = .002).

Keywords: Anxiety; cancer; coping; depression; geriatric oncology.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Aged
  • Anxiety
  • Brazil / epidemiology
  • Depression* / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms* / drug therapy