Objectives: To observe the clinical efficacy of timing umbilical therapy for neurogenic bladder after spinal cord injury based on the midnight-noon and ebb-flow doctrine.
Methods: Sixty patients with neurogenic bladder after spinal cord injury were randomly divided into a trial group and a control group, with 30 patients in each group. In the trial group, based on the midnight-noon and ebb-flow doctrine, umbilical therapy was given at the time zone, 15:00 to 17:00. In the control group, umbilical therapy was delivered at any time zones except the period 15:00 to 17:00. The herbal plaster was remained on the umbilicus for 4 h each time, once daily. One course of treatment was composed of 2 weeks and the treatment lasted 4 weeks. Before and after treatment, the urodynamic indexes (maximum urinary flow rate [Qmax], maximum detrusor pressure [Pdet-max], residual urine volume [RUV]), voiding diary (average daily number of voiding, average daily number of leakage, average daily voided volume), neurogenic bladder symptom score (NBSS), the score of urinary symptom distress scale (USDS) and the score of World Health Organization quality of life assessment-BREF (WHOQOL-BREF) were compared between the two groups; and the clinical efficacy of the two groups was assessed.
Results: After treatment, Qmax, Pdet-max, the average daily voided volume and the scores of WHOQOL-BREF were increased (P<0.05); and RUV, the average daily number of voiding, the average daily number of leakage, NBSS and the scores of USDS were all reduced (P<0.05) in comparison with those before treatment in the two groups. When compared with those in the control group, Qmax, Pdet-max, the average daily voided volume and the score of WHOQOL-BREF were all higher (P<0.05); and RUV, the average daily number of voiding, the average daily number of leakage, NBSS and the score of USDS were lower (P<0.05) in the trial group. The total effective rate was 96.7% (29/30) in the trial group, higher than that (76.7%, 23/30) in the control group (P<0.05).
Conclusions: Timing umbilical therapy, based on the midnight-noon and ebb-flow doctrine, effectively relieves the symptoms of dysuria and improves the quality of life in patients with neurogenic bladder after spinal cord injury.
目的: 观察基于子午流注理论择时脐疗治疗脊髓损伤后神经源性膀胱的临床疗效。方法: 将60例脊髓损伤后神经源性膀胱患者随机分为子午流注脐疗组和其他时间脐疗组，每组30例。子午流注脐疗组根据子午流注纳子法于申时（15：00-17：00）行脐疗，其他时间脐疗组避开申时，于其他时间行脐疗，均每次贴敷4 h，每日1次，2周为一疗程，连续治疗4周。比较两组患者治疗前后尿流动力学指标［最大尿流率（Qmax）、最大逼尿肌压力（Pdet-max）、残余尿量（RUV）］、排尿情况（日均排尿次数、日均漏尿次数、日均单次排尿量）、神经源性膀胱症状评分（NBSS）、泌尿症状困扰量表（USDS）评分、世界卫生组织生存质量评估简表（WHOQOL-BREF）评分，并评定临床疗效。结果: 治疗后，两组患者Qmax、Pdet-max、日均单次排尿量、WHOQOL-BREF评分较治疗前增加（P<0.05），RUV、日均排尿次数、日均漏尿次数、NBSS及USDS评分均较治疗前减少（P<0.05）；子午流注脐疗组患者Qmax、Pdet-max、日均单次排尿量、WHOQOL-BREF评分均高于其他时间脐疗组（P<0.05），RUV、日均排尿次数、日均漏尿次数、NBSS及USDS评分均低于其他时间脐疗组（P<0.05）。子午流注脐疗组总有效率为96.7%（29/30），高于其他时间脐疗组的76.7%（23/30，P<0.05）。结论: 基于子午流注理论择时脐疗可有效改善脊髓损伤后神经源性膀胱患者排尿困难症状，提高其生活质量。.
Keywords: midnight-noon and ebb-flow doctrine; neurogenic bladder; spinal cord injury; treatment timing; umbilical therapy.