The potential of BRD4 inhibition in tumour mechanosignaling

J Cell Mol Med. 2023 Dec;27(24):4215-4218. doi: 10.1111/jcmm.18057. Epub 2023 Nov 23.

Authors

Antonios N Gargalionis¹, Kostas A Papavassiliou², Athanasios G Papavassiliou³

Affiliations

¹ Department of Biopathology, 'Eginition' Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
² First University Department of Respiratory Medicine, 'Sotiria' Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
³ Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

No abstract available

Keywords: BRD4; TAZ; YAP; mechanosignaling; targeted therapy; tumour inhibitor.

MeSH terms

Adaptor Proteins, Signal Transducing / metabolism
Bromodomain Containing Proteins
Cell Cycle Proteins / genetics
Humans
Neoplasms* / drug therapy
Nuclear Proteins / genetics
Phosphoproteins / metabolism
Transcription Factors* / genetics
Transcription Factors* / metabolism

Substances

Transcription Factors
Nuclear Proteins
Adaptor Proteins, Signal Transducing
Phosphoproteins
BRD4 protein, human
Bromodomain Containing Proteins
Cell Cycle Proteins