selscan 2.0: scanning for sweeps in unphased data

Bioinformatics. 2024 Jan 2;40(1):btae006. doi: 10.1093/bioinformatics/btae006.

Abstract

Summary: Several popular haplotype-based statistics for identifying recent or ongoing positive selection in genomes require knowledge of haplotype phase. Here, we provide an update to selscan which implements a re-definition of these statistics for use in unphased data.

Availability and implementation: Source code and binaries are freely available at https://github.com/szpiech/selscan, implemented in C/C++, and supported on Linux, Windows, and MacOS.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Genome*
  • Haplotypes
  • Software*