Diterpenoid Alkaloids from Delphinium liangshanense

Yue Liu; Yi-Dan Zhao; He-Yang Zhong; Si-Yang Chen; Shuai Huang; Lin Chen; Xian-Li Zhou

doi:10.1002/cbdv.202301923

Diterpenoid Alkaloids from Delphinium liangshanense

Chem Biodivers. 2024 Jan 8:e202301923. doi: 10.1002/cbdv.202301923. Online ahead of print.

Authors

Yue Liu¹, Yi-Dan Zhao¹, He-Yang Zhong¹, Si-Yang Chen¹, Shuai Huang^{1

2}, Lin Chen^{1

2}, Xian-Li Zhou^{1

3

2}

Affiliations

¹ School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, Sichuan, People's Republic of China.
² School of Life Science and Engineering, Yibin Institute of Southwest Jiaotong University, Yibin, 644000, Sichuan, People's Republic of China.
³ Affiliated Hospital of Southwest Jiaotong University & The Third People Hospital of Chengdu, Chengdu, 610031, Sichuan, People's Republic of China.

PMID: 38191840
DOI: 10.1002/cbdv.202301923

Abstract

Two new C₁₉-diterpenoid alkaloids of the lycoctonine-type (liangshanine A and liangshanine B) and nineteen known compounds (3-21) were isolated from the whole plant of Delphinium liangshanense W. T. Wang, and all the compounds were identified by different spectroscopic analyses, such as IR, HR-ESI-MS and NMR. All the compounds were isolated from this plant for the first time and tested for the anti-proliferation effects on MH7 A and SF9 cells to figure their anti-rheumatoid arthritis and anti-insect activity, but none of them showed remarkable activity.

Keywords: C19-diterpenoid alkaloids; Delphinium liangshanense; Ranunculaceae; liangshanine B; liangshanine A.

Abstract

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