Increased incidence of adult gonococcal keratoconjunctivitis at two tertiary eye hospitals in Western Europe: clinical features, complications and antimicrobial susceptibility

Br J Ophthalmol. 2024 May 21;108(6):788-792. doi: 10.1136/bjo-2023-324750.

Abstract

Background: Gonorrhoea is on the rise: between 2021 and 2022, a 50% and a 33% increase in diagnoses was seen, respectively, in England and the Netherlands. A concurrent rise in gonococcal keratoconjunctivitis (GKC) is a serious concern due to the potentially devastating visual complications.

Methods: This is a retrospective case series of adult GKC from two Western European tertiary ophthalmology centres between 2017 and July 2023. The clinical features, ocular complications and antimicrobial susceptibilities are reported within.

Results: An increased incidence was recorded at both centres, with 11 confirmed cases in the first 7 months of 2023, compared with ≤3 per year in 2017-2022.

Conclusion: The notable increase of GKC cases in our centres in 2023 may indicate a rise across Western Europe. Enhanced, sustained, national surveillance of GKC is essential to establish incidence and antimicrobial susceptibility, to inform treatment guidelines and guide appropriate public health response.

Keywords: Cornea; Infection; Public health.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents* / therapeutic use
  • Europe / epidemiology
  • Eye Infections, Bacterial* / drug therapy
  • Eye Infections, Bacterial* / epidemiology
  • Eye Infections, Bacterial* / microbiology
  • Female
  • Gonorrhea* / drug therapy
  • Gonorrhea* / epidemiology
  • Gonorrhea* / microbiology
  • Humans
  • Incidence
  • Keratoconjunctivitis* / drug therapy
  • Keratoconjunctivitis* / epidemiology
  • Keratoconjunctivitis* / microbiology
  • Male
  • Microbial Sensitivity Tests*
  • Middle Aged
  • Neisseria gonorrhoeae* / drug effects
  • Neisseria gonorrhoeae* / isolation & purification
  • Retrospective Studies
  • Tertiary Care Centers* / statistics & numerical data
  • Young Adult