Cytomorphology of metastatic malignant peripheral nerve sheath tumour present in pleural fluid: Case study and literature review

Cytopathology. 2024 May;35(3):398-403. doi: 10.1111/cyt.13371. Epub 2024 Mar 5.

Abstract

The cytomorphology of MPNST in effusion specimens is rarely described. In this paper, the detailed cytopathological and immunohistochemical characteristics of metastatic MPNST has been described in pleural effusion. Patients' medical history and the judicious utilization of ancillary studies contribute to ensure precise cytological diagnoses. The cytomorphology of malignant peripheral nerve sheath tumour (MPNST) in effusion specimens can be diagnostically challenging. The author presents detailed cytopathological and immunohistochemical characteristics of a case of metastatic MPNST in pleural effusion.

Keywords: cytology; malignant peripheral nerve sheath tumour; pleural effusion; pleural fluid.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Humans
  • Neoplasms, Second Primary*
  • Neurofibrosarcoma*
  • Pleural Effusion*
  • Pleural Effusion, Malignant* / diagnosis
  • Pleural Effusion, Malignant* / pathology