Squamous cell carcinoma of breast metastasising to upper lip

BMJ Case Rep. 2024 Mar 4;17(3):e259653. doi: 10.1136/bcr-2024-259653.

Abstract

Breast cancer is a heterogeneous set of carcinomas comprising a subgroup of invasive ductal carcinomas and numerous infrequent subtypes. Primary squamous cell carcinoma (SCC) breast is sporadic, accounting for less than 0.1% of all invasive subtypes. Primary metastases to soft tissues of the oral cavity are incredibly rare, amounting to 0.1% of oral malignancies. Diagnosing metastasis to the oral cavity is an enigma to clinicians without pathognomonic signs and symptoms. Here, we report a case of SCC breast, who developed metastatic deposits in the left upper lip after a disease-free survival of 1 year. There are no reports of SCC breast metastasising to the oral cavity, and probably, this is the first such case getting reported. The survival of such patients is abysmal, with most cases surviving less than a year post diagnosis. While treating patients with a history of malignancy, a high degree of clinical presentiment is required.

Keywords: Breast cancer; Chemotherapy; Head and neck cancer; Oncology.

Publication types

  • Case Reports

MeSH terms

  • Breast
  • Breast Neoplasms*
  • Carcinoma, Squamous Cell* / diagnosis
  • Female
  • Humans
  • Lip
  • Mouth Neoplasms* / diagnosis