Cardiovascular disease risk scores in patients with optimal vs suboptimal weight loss after bariatric surgery: Translating improvements into clinical practice

Am J Surg. 2024 Jul:233:136-141. doi: 10.1016/j.amjsurg.2024.03.009. Epub 2024 Mar 11.

Abstract

Introduction: The aim of this study was to evaluate cardiovascular disease (CVD) risk modification in patients with optimal weight loss (OWL) versus suboptimal weight loss SWL following MBS.

Methods: This was a retrospective analysis. The 10-year risk CVD was estimated before and after one year of surgery using the "Framingham Score".

Results: 191 patients were included in our study. Mean baseline Framingham score was 7.2 ​± ​6.9%. According to the score, 54% of patients were classified as low risk (n ​= ​104), 23% as moderate (n ​= ​43), 20% moderately high (n ​= ​39) and 3% as high risk (n ​= ​5). One year after surgery, 91% of the patients showed reduction of their Framingham score. Mean CVD risk score decreased significantly to 4.1 ​± ​3.7% when compared to baseline (p-value is ​< ​0.001); 80% of patients classified as low risk (n ​= ​153), 13% as moderate (n ​= ​25), 7% moderately high (n ​= ​13) and 0% as high risk (n ​= ​0).

Conclusion: Weight loss after bariatric surgery reduces CVD risk scores and the magnitude of effect correlates with the degree of weight loss.

Keywords: Bariatric surgery; Cardiovascular disease; Cardiovascular risk scores; Roux-en-Y gastric bypass; Sleeve gastrectomy; Weight loss.

MeSH terms

  • Adult
  • Bariatric Surgery*
  • Cardiovascular Diseases* / etiology
  • Cardiovascular Diseases* / prevention & control
  • Female
  • Heart Disease Risk Factors
  • Humans
  • Male
  • Middle Aged
  • Obesity, Morbid / complications
  • Obesity, Morbid / surgery
  • Retrospective Studies
  • Risk Assessment
  • Weight Loss*