MINOCA: Myocardial infarction no obstructive coronary artery disease

Hooman Bakhshi; C Michael Gibson

doi:10.1016/j.ahjo.2023.100312

MINOCA: Myocardial infarction no obstructive coronary artery disease

Am Heart J Plus. 2023 Jul 29:33:100312. doi: 10.1016/j.ahjo.2023.100312. eCollection 2023 Sep.

Authors

Hooman Bakhshi¹, C Michael Gibson²

Affiliations

¹ Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
² Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Abstract

Myocardial infarction without obstructive coronary artery disease (MINOCA) is defined as myocardial infarction with mild or no obstructive coronary artery disease (CAD) on angiogram. MINOCA has a number of heterogeneous causes, including coronary disruption, coronary vasospasm, coronary embolism, spontaneous coronary artery dissection (SCAD), and coronary microvascular dysfunction (CMD). Even though MINOCA might have a better prognosis than MI with obstructive CAD, it is not benign. A stepwise diagnostic approach is crucial to identifying the underlying cause of MINOCA or conditions mimicking it. A cause-specific treatment approach is the key to managing MINOCA.

Keywords: Cardiac MRI; IVUS; MINOCA; OCT; SCAD.

Publication types

Review